UriDetox

Female urinary health is a key aspect of overall well-being. Urinary tract infections (UTIs) affect at least 50-60% of women at some point in their life, and approximately 20-30% of them suffer frequent recurrences (more than 3 episodes per year).¹.

These infections usually manifest with:

• Burning or stinging when urinating.
• Urgency and increased urinary frequency.
• Pelvic pain or low pressure.
• Discomfort during sexual intercourse.

The causes are multifactorial:

• Short urethra and close to the anus, which facilitates the entry of bacteria.².
• Sexual activity without subsequent urination³.
• Alterations in the vaginal/urinary microbiota⁴.
• Menopause and estrogen deficiency⁵.
• Excessive use of antibiotics, which promotes resistance⁶.

All of this creates a chronic inflammatory environment where bacteria perpetuate and the mucosa loses its integrity and protection.

UriDetox of Vitobest® is a natural and advanced formula that acts on all fronts:

• Prevents adhesion of E. coli to the urinary epithelium⁷.
• Restores the vaginal microbiota with specific strains⁸.
• Reduces inflammation and oxidative damage⁹.
• Promotes a cleaner urinary flow⁹.
• It does not alter the flora or cause resistances.

Synergistic action with key ingredients:

• D-Mannose:Natural monosaccharide that is excreted in urine. It blocks the adhesion of E. coli to the urothelium by competing with the mannose receptors of the epithelium⁷. It facilitates the natural elimination of bacteria and prevents its colonization.
• ProCran® (American cranberry): standardized extract with 3% of proanthocyanidins (PACs) type A^3,4. It prevents the fixation of bacteria, protects the urinary epithelium and has antioxidant action against chronic inflammation.
• Ext. HibiscusHibiscus syriacus): extract with a 36% of proanthocyanidins (PACs) with diuretic, anti-inflammatory and antioxidant action⁹. Improves urinary flow, modulates inflammation, and helps to make the environment more difficult for bacteria.
• Lactobacillus rhamnosus LR32 and Lactobacillus reuteri This text is incomplete. Could you please provide the full text for translation? clinically validated strains to restore vaginal and urinary microbiota^8,10. They produce lactic acid and bacteriocins, maintain the vaginal pH acidic, and prevent the adhesion of pathogens.

UriDetox, your natural ally to prevent and treat urinary infections. It protects, rebalances and strengthens your urogenital health from within.

Bibliography:

¹Foxman, B. (2014). Urinary tract infection syndromes: occurrence, recurrence, bacteriology, risk factors, and disease burden. Infect Dis Clin North Am.

²Naber, K. G. et al. (2009). Pathogenesis of UTIs: anatomical and physiological aspects. Int J Antimicrobial Agents.

³Scholes, D. et al. (2000). Risk factors for recurrent UTIs in young women. N Engl J Med.

⁴Jepson, R. G. et al. (2012). Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev.

⁵Raz, R. (2011). UTIs in postmenopausal women. Clin Geriatr Med.

⁶Ventola, C. L. (2015). The antibiotic resistance crisis: part 1: causes and threats. Pharm Ther.

⁷Kranjčec, B. et al. (2014). D-mannose powder for prevention of recurrent urinary tract infections. World J Urol.

⁸Reid, G. et al. (2003). Dose of Probiotic Lactobacillus required to restore and maintain normal vaginal flora. FEMS Immunology Medical Microbiology.

⁹Hopkins, A. L. et al. (2013). Hibiscus sabdariffa and inflammation: a systematic review. Phytotherapy.

¹⁰Beerepoot, M. A. J. et al. (2012). Lactobacilli vs. Antibiotics to Prevent Urinary Tract Infections: A Randomized Trial. Arch Intern Med.