Myo+D-Chiro Inositol Complex

The Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects between 6% and 20% of women of reproductive age and is on the rise^1,2.

• Irregular or non-existent periods.
• Presence of ovarian cysts.
• Overweight or obesity.
• Symptoms such as acne, increased hair or hair loss³.

These are some of the most characteristic symptoms of PCOS that many women of reproductive age present, without being aware of the metabolic and hormonal alterations behind them^4,5. In addition, due to a sedentary lifestyle, diets high in processed foods, high levels of stress, and exposure to endocrine disruptors, the prevalence and severity of PCOS is increasing.

For this reason, Vitobest® has created Myo+D-Chiro Inositol Complex, a product specifically thought and formulated to provide our body with all the necessary tools to face PCOS and the symptoms it causes.

Myo+D-Chiro Inositol Complex, from Vitobest®, is a formula that combines the most advanced and effective natural active ingredients to help regain a hormonal and metabolic balance that PCOS has altered⁶:

• Myo-Inositol: regulates insulin and promotes ovulation, helping to restore menstrual regularity and reduce PCOS symptoms⁷.
• D-Chiro-Inositol: together with Myo-Inositol in an optimal ratio of 40:1, works synergistically to improve insulin sensitivity and reduce androgens, supporting metabolism and hormonal balance⁸.
• Zinc Bisglycinate (Albion™): supports hormonal balance and reduces androgens to improve symptoms of hyperandrogenism; its chelated form ensures high absorption and prevents gastrointestinal effects⁹.
• Shilajit (ShilaZen®, 50% fulvic acid): acts as an adaptogen and antioxidant to reduce stress and improve insulin sensitivity; ShilaZen® guarantees purity and safety¹⁰.
• Resveratrol: anti-inflammatory and hormonal regulator that improves insulin sensitivity, reducing androgen production and PCOS symptoms¹¹.

Balance your body and fight PCOS with the advanced natural formula of Myo+D-Chiro Inositol Complex, from Vitobest®!

Bibliography:

¹Ding, T., Hardiman, P. J., Petersen, I., Wang, F. F., Qu, F., & Baio, G. (2017). The prevalence of polycystic ovary syndrome in reproductive-aged women of different ethnicity: a systematic review and meta-analysis. Oncotarget, 8(56), 96351. doi:10.18632/oncotarget.19180

²Azziz, R., Carmina, E., Chen, Z., Dunaif, A., Laven, J. S., Legro, R. S., & Yildiz, B. O. (2016). Polycystic ovary syndrome. Nature Reviews Disease Primers, 2(1), 1-18. doi:10.1038/nrdp.2016.57

³Fauser, B. C., Tarlatzis, B. C., Rebar, R. W., Legro, R. S., Balen, A. H., Lobo, R., ... & Boivin, J. (2012). Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM‐Sponsored 3rd PCOS Consensus Workshop Group. Fertility and Sterility, 97(1), 28-38. doi:10.1016/j.fertnstert.2011.09.024

⁴Diamanti-Kandarakis, E., & Dunaif, A. (2012). Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocrine Reviews, 33(6), 981-1030. doi:10.1210/er.2011-1034

⁵Gibson-Helm, M., Teede, H., Dunaif, A., & Dokras, A. (2017). Delayed diagnosis and a lack of information associated with dissatisfaction in women with polycystic ovary syndrome. Journal of Clinical Endocrinology & Metabolism, 102(2), 604-612. doi:10.1210/jc.2016-2963

⁶Nestler, J. E., & Unfer, V. (2015). Reflections on inositol(s) for PCOS therapy: steps toward success. Gynecological Endocrinology, 31(7), 501-505. doi:10.3109/09513590.2015.1016186

⁷D'Anna, R., Santamaria, A., Cannata, M. L., Interdonato, M. L., Corrado, F., & Benedetto, A. D. (2007). Myo‐inositol supplement may improve oocyte quality in intracytoplasmic sperm injection cycles for PCOS women. European Review for Medical and Pharmacological Sciences, 11(6), 423-426.

⁸Isabella, R., & Raffone, E. (2012). Does ovary need D-chiro-inositol? Journal of Ovarian Research, 5(1), 14. doi:10.1186/1757-2215-5-14

⁹Hambidge, K. M., & Krebs, N. F. (2007). Zinc deficiency: a special challenge. Journal of Nutrition, 137(4), 1101-1105. doi:10.1093/jn/137.4.1101

¹⁰Schepdael, A., De Spiegeleer, B., & Braeken, E. (2008). The analysis and health benefits of shilajit. Journal of Natural Medicine, 62(4), 431-438. doi:10.1007/s11418-008-0251-6

¹¹Vyas, N., Polotsky, A. J., & Smits, R. M. (2020). The role of antioxidants in the pathophysiology and treatment of polycystic ovary syndrome: A systematic review and meta-analysis. Fertility and Sterility, 113(6), 1370-1383. doi:10.1016/j.fertnstert.2020.02.129