V-Col

V-Col, from Vitobest®, It is an advanced formula 100% natural based on extracts of the highest quality plants to aid cardiovascular health and cholesterol control.

The amount of cholesterol is one of the main indicators of cardiovascular risk. The risk of suffering from any of these diseases not only depends on how much cholesterol we have, but also on "what type" of cholesterol we have in our blood. High levels of LDL (the bad cholesterol) are associated with a high cardiovascular risk; on the contrary, high levels of HDL significantly reduce the risk.

V-Col, from Vitobest®, it operates in three phases simultaneously:

• Helping to reduce levels of LDL (bad) cholesterol^1,2.
• Contributing to improving cardiovascular health through the reduction of atheroma plaques and cardiac function¹.
• Helping to increase overall metabolic activity and especially lipid metabolism^1,2.

V-Col, from Vitobest®, uses in its composition patented natural extracts of:

1. Bergavit™. Dry extract of Bergamot: It helps to reduce and control the levels of bad lipids in plasma (total cholesterol, LDL and triglycerides). It also contributes to increasing the levels of HDL (good cholesterol).

1.1. The flavonoids of Bergavit™ reduce cardiovascular risk:

• They help improve coronary vasodilation.
• They contribute to improving blood circulation.
• They help prevent the oxidation of LDL.

1.2. Mechanism of action of Bergavit™:

• Contributes to activating the oxidative pathway of the mitochondria.
• Helps reduce the synthesis of VLDL and lipoproteins.
• Contributes to activating metabolic pathways.

1.3. Effect of consumption Bergavit™:

• The daily intake of 600 mg of Bergavit™ helps to significantly reduce "bad" LDL cholesterol¹.

2. Capros®. Dry extract of amla fruit: helps to increase the production of nitric oxide and glutathione⁶. It has a recognized antioxidant power that helps improve endothelial dysfunction.⁶.

Studies show that Capros® It also helps to increase HDL levels and effectively reduce triglyceride and LDL levels, minimizing cardiovascular risk factors⁶.

3. Mediteanox® (15% hydroxytyrosol). Dry extract from olive fruit: Powerful anti-inflammatory effective in endothelial dysfunction that helps improve coagulation and regulate blood lipids.⁷.

• Helps to reduce oxidative cellular stress.
• Contributes to improving circulation.
• Helps regulate cholesterol levels⁷.
• Improves arterial health⁷.

4. Berberine (HCI 97%). Dry extract of Berberis aristata: contributes to regulating blood glucose levels³ and to control lipids.

5. Dry extract of White Hawthorn (10:1): Thanks to its sterols and triterpenes, it constitutes an anti-sclerotic.⁴. It is also useful for controlling blood pressure and diabetes by inhibiting phosphodiesterase^4,5.

6. Sugar cane policosanols (98% policosanol and 10% octacosanol): they contribute to reducing levels of LDL and triglycerides in the blood⁸.

V-Col Vitobest® contributes to:

Vitobest® used for this supplement vegetable capsules (VegeCaps) suitable for vegan diets and free of titanium dioxide.

Bibliography:

¹"Bergamot reduces plasma lipids, atherogenic small dense LDL, and subclinical atherosclerosis in subjects with moderate hypercholesterolemia: a 6 month prospective study". Peter, P. et al.

²"Hypolipidemic effects of" Citrus bergamia Risso "and Poiteau juice in rats fed a hypercholesterolemic diet". 2007. Miceli, N. J. et al. Agric. Food Chem. 55, 10671-10677. DOI: 10.1021/jf071772i.

³"Antihyperglycemic activity of root of" Berberis aristata d.c. "in alloxan induced diabetic rat". 2009. Semwal, B.C. et al. Int. J of Green Pharmacy. Jul-Sept; 259-63.

⁴“Composition and health effects of phenolic compounds inh awthorn (Cratae gusspp.) of different origins”. Baoru Yang & Pengzhan Liu. DOI: 10.1002/jsfa.5671.

⁵“Effects of haw thornoncardiac remode lingand left ventricular dysfunction after 1month of pressure overload - induced cardiac hypertrophyin rats”. 2008. Hwang, H.S. et al. Cardiovasc DrugsTher 22:19–28.

⁶"Evaluation of the effects of a standardized aqueous extract" Phyllanthus emblica "Fruits on endothelial dysfunction, oxidative stress, systemic inflammation and lipid profile in subjects with metabolic syndrome: a randomised, double-blind, placebo-controlled clinical study". Pingali, U. et al.

⁷"Supplementation with Hydroxytyrosol and Punicalagin improves early atherosclerosis markers involved in the asymptomatic phase of atherosclerosis in the adult population: a randomized, placebo-controlled, crossover trial". Quirós-Fernández, R. et al.

⁸"Studies on Cytoprotective and Antioxidant Activity of Jaggery Sugar". 2009. Harish Nayaka, M.A. et al. Food Chem.; 115:113–8.