PQQ

PQQ, from Vitobest®, contains pyrroloquinoline quinone (PQQ), one of the most promising nutrients in the field of cellular nutrition. Its action is focused on the mitochondria, authentic power plants of our cells, responsible for producing more than 90% of the energy we use daily¹.

Over time, mitochondria decrease in number and efficiency, which translates into fatigue, decreased vitality, cognitive decline, and cardiovascular problems^2,3. PQQ, from Vitobest®, offers a unique solution: it stimulates the mitochondrial biogenesis, that is, the creation of new mitochondria, and at the same time protects the existing ones against oxidative damage^4,5,17.

Unlike other antioxidants that are consumed after neutralizing a free radical, PQQ acts like a catalytic antioxidant, capable of regenerating and continuing to protect continuously. This characteristic makes it a key ally against the chronic oxidative stress, one of the main drivers of cellular aging⁶.

In addition to its impact on energy, PQQ exerts a powerful neuroprotective action, promoting communication between neurons, synaptic plasticity, and memory. This translates into an improvement in the concentration, mental clarity and learning ability, while also protecting against age-related cognitive decline^7,15.

In the field cardiovascular, PQQ helps to improve endothelial function, optimize blood flow and reduce vascular inflammation, thus contributing to the protection of the heart and a more efficient circulation^8,16. It also modulates the metabolism of fats and sugars, promoting a more stable energy balance and reducing the low-grade inflammation that accompanies aging^9,13.

The formula of Vitobest® use the disodium form of PQQ, the most stable, bioavailable, and studied in clinical trials, which ensures that each capsule provides the maximum efficacy and safety^10,12,14.

With PQQ, from Vitobest®, a step forward is taken in the innovation in mitochondrial supplementation, offering a product designed for those seeking more energy, improved mental and physical performance, cardiovascular protection, and healthy longevity.

Vitobest® used for this supplement vegetable capsules (VegeCaps) suitable for vegan diets and free from titanium dioxide.

Bibliography:

¹Nicholls DG, Ferguson SJ. Bioenergetics 4. Academic Press; 2013.

²Chistiakov DA, et al. Cell Mol Life Sci. 2018;75(6):1301-1326.

³López-Otín C, et al. "The hallmarks of aging." Cell. 2013;153(6):1194-1217.

⁴Rucker R, Chowanadisai W. Exp Biol Med. 2009;234(12):1290-1293.

⁵Chowanadisai W, et al. J Biol Chem. 2010;285(1):142-152.

⁶Akagawa M, et al. J Nutritional Science and Vitamins. 2016;62(1):1-5.

⁷Kumar V, et al. Neurochem Int. 2017;104:115-122.

⁸Harris CB, et al. Nutrients. 2013;5(6):2081-2092.

⁹Rucker RB. Biofactors. 2008;36(4):274-282.

¹⁰Ohwada K, et al. Regulatory Toxicology and Pharmacology. 2015;73(3):725-734.

¹¹Stites T, et al. J Nutr Biochem. 2006;17(8):493-502.

¹²Harris CB, et al. Altern Med Rev. 2014;19(1):3-10.

¹³Nakano M, et al. Funct Foods Health Dis. 2015;5(6):187-203.

¹⁴Nakano M, et al. Food Style. 2009;13(7):50-53.

¹⁵Yang Y, et al. Brain Res. 2018;1679:84-92.

¹⁶Kasahara T, et al. J Clin Biochem Nutr. 2013;52(3):166-173.

¹⁷Rucker RB. Biofactors. 2008;36(4):274-282.