Nattokinase

Maintaining good circulation is essential for overall well-being. Sedentarism, stress and the passage of time can affect vascular health, which is why more and more people decide to act before problems arise. Taking care of circulation today is investing in tomorrow's cardiovascular balance.

That's why Vitobest® has formulated Nattokinase, a practical and standardized solution for those seeking natural and continuous support.

Nattokinase is an enzyme obtained from natto, a traditional Japanese food made from fermented soybeans. It was first identified in 1987 by Dr. Hiroyuki Sumi, who described its fibrinolytic activity¹. Since then, it has been studied for its ability to intervene in natural mechanisms related to fibrin and blood fluidity².

Human trials have shown that nattokinase supplementation can be associated with reductions in markers such as fibrinogen, factor VII, and factor VIII, parameters involved in circulatory dynamics³. Other clinical studies have observed improvements in blood pressure when used continuously within a healthy lifestyle⁴.

In addition, recent scientific reviews highlight its potential within global cardiovascular prevention strategies, especially due to its non-pharmacological action profile and its easy integration into daily routines⁵.

In nattokinase, not only the milligrams are important, but also its real activity. FUs (Fibrinolytic Units) measure the effective enzymatic power. With 2000 FUs per capsule, Vitobest® guarantees a standardized and constant dose, ensuring true biological activity in each intake.

Vitobest® uses for this supplement vegetable capsules (VegeCaps) suitable for vegan diets and free of titanium dioxide.

Bibliography:

¹Sumi H. et al. (1987). A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto. Experientia, 43(10), 1110–1111.

²Urano T. et al. (2001). The profibrinolytic enzyme nattokinase. Pathophysiology of Haemostasis and Thrombosis, 31(3–6), 164–168.

³Hsia C.H. et al. (2009). Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects. Nutrition Research, 29(3), 190–196.

⁴Kim J.Y. et al. (2008). Effects of nattokinase on blood pressure: a randomized, controlled trial. Hypertension Research, 31(8), 1583–1588.

⁵Weng Y. et al. (2017). Nattokinase: An oral antithrombotic agent for the prevention of cardiovascular disease. International Journal of Molecular Sciences, 18(3), 523.