Post Training

The most important phase of sports activity, which defines success and the ability to achieve our goals, is the post-training phase. After strenuous physical activity, our bodies and muscles have suffered damage at the muscular and joint level, just as they have exhausted various energy substrates, minerals, and amino acids to overcome the effort to which they have been subjected.

Vitobest®, with the aim of enhancing the recovery of our muscles and our body, has formulated Post Training, one of the most comprehensive post-workout supplements on the market that offers maximum recovery, acting from all fronts:

• Repair of protein structures at the muscular and joint level.
• Relaxation and recovery of the nervous system.
• Anti-inflammatory action.
• Replenishment of minerals and amino acids.

Post Training from Vitobest® includes:

• Clonapure® Creatine: Creatine in its active form, phosphocreatine, is much more effective and provides immediate energy. Creatine mainly acts through its effects on energy metabolism, regenerating cellular ATP¹. In this way, it improves strength and power during endurance exercise, as well as increases lean mass². Numerous studies in athletes confirm their ability to reduce body fat and improve anaerobic exercise performance, strength, and power output³. It also reduces mental fatigue in times of sleep deprivation or exercise to exhaustion⁴.
  

   

  

   

• L-Glutamine: the most abundant amino acid in our body and conditionally essential, which means it is necessary during conditions of high physical stress, decreasing its concentration in these circumstances⁵. For this reason, a contribution of L-Glutamine during intense and prolonged physical activity maintains its concentrations in the blood in a stable manner, favoring its multiple functions in our body^6.7:
  
  1 > Acts as a nitrogen transporter at the muscular level, promoting recovery.
  2 > Precursor of the antioxidant glutathione.
  3 > Regulates acid/base metabolism, preventing states of acidosis.
  4 > It participates as a substrate in gluconeogenesis, a process in which glucose is obtained as a source of energy.
  5 > Stimulates the production of L-Citrulline and L-Glycine acting as a substrate, promoting vasodilation and hydration.
  

   

  

   

• BCAA 4:1:1: Essential amino acids are basic components of proteins that the body is not capable of producing, but needs to acquire through diet to ensure its proper functioning and development. The BCAAs are the three most abundant essential amino acids in muscle tissue: L-Leucine, L-Valine, and L-Isoleucine. They differ from other essential amino acids because they have a branched side chain and play an important role in stimulating protein synthesis, being the most anabolic amino acids⁸. Among its effects on athletic performance, we can find^9,10,11:
  
  1 > Improvement in athletes' performance by promoting increased muscle mass and strength.
  2 > Accelerates the use of fats as a source of energy, preserving muscle glycogen.
  3 > It reduces the synthesis of serotonin in the brain, which is the cause of the feeling of fatigue after exercise.
  4 > Improves recovery and reduces muscle damage after exercise.
  
  
• Hydroxymethylbutyrate (HMB): HMB is an active metabolite of the essential amino acid leucine that plays an anticatabolic role in muscle tissue. HMB stimulates protein synthesis, being effective in reducing muscle damage associated with sports activity after high-intensity exercise¹².
  

   

  

   

• Glucosamine sulfate and chondroitin sulfate: basic components of cartilage and synovial fluid, with anti-inflammatory and protective properties to prevent and treat joint injuries.
  
  > Glucosamine is an amino-monosaccharide that is highly concentrated in connective tissues and cartilage. The body uses glucosamine to synthesize the structural components present in both cartilage and joints, and they play a crucial role in providing elasticity, strength, and flexibility to these tissues¹³. Additionally, it inhibits the inflammatory cascade involved in the degradation of collagen in joint tissues, preventing their deterioration¹⁴.
  
  > Chondroitin sulfate is naturally found in cartilage, where it helps prevent tissue degradation and provides mechanical support to the joints¹⁵. Chondroitin is hydrophilic and attracts water to the cells, which aids in hydration and mechanical support of the joints. It also helps the cells that form cartilage to regenerate more efficiently and slows down their death. Chondroitin also has anti-inflammatory effects, inhibiting the expression of pro-inflammatory immune factors¹⁶.
  
  
• Methylsulfonylmethane (MSM): Methylsulfonylmethane (MSM) is an organosulfur compound capable of controlling chronic inflammation, in addition to having antioxidant effects at the lipid and protein level, improving joint pain^17,18.
  

   

  

   

• Sodium citrate, potassium citrate, and calcium bisglycinate: Ions are essential for a wide variety of metabolic processes in our bodies. High-intensity or prolonged workouts can lead to their loss, causing temporary deficiencies that directly affect the proper functioning of our muscles and nervous system, negatively impacting our physical and mental state. Therefore, correctly replenishing these ions is key to reducing our sensation of fatigue and maintaining our performance.
  
  
• Magnesium bisglycinate: Magnesium is one of the most abundant minerals in the body, acting as an electrolyte and cofactor for more than 300 enzymes. At the muscular level, it acts as an endogenous blocker of calcium channels, helping to regulate muscle contraction. It is known that magnesium depletion induces cramps and severe muscle pain, which is why its replenishment after physical activity is fundamental^19,20. Moreover, on a hormonal level, magnesium can increase or normalize testosterone levels in the blood, promoting anabolism and muscle recovery²¹.

Post Training features:

The repair of muscle damage, regeneration of affected tissues, reduction of inflammation caused during sports activity, and replenishment of various components used after training is the key to proper recovery to face the next challenge, the key to Post Training, from Vitobest®.

Bibliography:

¹Kent Sahlin, Roger C HarrisThe creatine kinase reaction: a simple reaction with functional complexityAmino Acids.(May 2011)

²Branch JD Effect of creatine supplementation on body composition and performance: a meta-analysis Int J Sport Nutr Exerc Metab. (June 2003)

³Wu Y, Hu X, Chen L Effects of Creatine in Trained Athletes: A Meta-analysis of 21 Randomized Placebo-Controlled Trials.Am J Ther.(2020)

⁴Forbes SC, Cordingley DM, Cornish SM, Gualano B, Roschel H, Ostojic SM, Rawson ES, Roy BD, Prokopidis K, Giannos P, Candow DG. Effects of Creatine Supplementation on Brain Function and Health.Nutrients.(2022-Feb-22)

⁵Lacey JM, Wilmore DW. Is glutamine a conditionally essential amino acid? Nutr Rev. (1990 Aug)

⁶Gleeson M. Dosage and efficacy of glutamine supplementation in human exercise and sport training. J Nutr. (October 2008)

⁷Fujita T, Yanaga K. Association between glutamine extraction and release of citrulline and glycine by the human small intestine. Life Sci. (April 24, 2007).

⁸Yoshizawa FNew therapeutic strategy for amino acid medicine: notable functions of branched chain amino acids as biological regulatorsJ Pharmacol Sci.(2012)

⁹Ahlborg G, Felig P, Hagenfeldt L, Hendler R, Wahren J. Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids. J Clin Invest. (April 1974)

¹⁰Shimomura Y, Murakami T, Nakai N, Nagasaki M, Obayashi M, Li Z, Xu M, Sato Y, Kato T, Shimomura N, Fujitsuka N, Tanaka K, Sato M. Suppression of glycogen consumption during acute exercise by dietary branched-chain amino acids in rats. J Nutr Sci Vitaminol (Tokyo). (April 2000)

¹¹Blomstrand EA role for branched-chain amino acids in reducing central fatigueJ Nutr. (February 2006)

¹²Jacob M Wilson, Peter J Fitschen, Bill Campbell, Gabriel J Wilson, Nelo Zanchi, Lem Taylor, Colin Wilborn, Douglas S Kalman, Jeffrey R Stout, Jay R Hoffman, Tim N Ziegenfuss, Hector L Lopez, Richard B Kreider, Abbie E Smith-Ryan, Jose Antonio International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)J Int Soc Sports Nutr. (February 2, 2013)

¹³Dahmer S, Schiller RMGlucosamine.Am Fam Physician. (August 15, 2008)

¹⁴Herrero-Beaumont G, Rovati LC, Castañeda S, Alvarez-Soria MA, Largo R. The reverse glucosamine sulfate pathway: application in knee osteoarthritis. Expert Opin Pharmacother. (Feb 2007)

¹⁵Pal D, Saha S. Chondroitin: a natural biomarker with immense biomedical applications. RSC Adv. (September 3, 2019)

¹⁶Brito R, Costa D, Dias C, Cruz P, Barros P. Chondroitin Sulfate Supplements for Osteoarthritis: A Critical Review. Review.Cureus.(June-2023)

¹⁷Ebisuzaki KAspirin and Methylsulfonylmethane (MSM): A Search for Common Mechanisms, with Implications for Cancer prevention.Anticancer Res. (2003)

¹⁸Nakhostin-Roohi B, Barmaki S, Khoshkhahesh F, Bohlooli S. Effect of chronic supplementation with methylsulfonylmethane on oxidative stress following acute exercise in untrained healthy men. J Pharm Pharmacol. (October 2011)

¹⁹Stephenson EW, Podolsky RJ. Regulation of intracellular calcium movement in skinned muscle fibers by magnesium. J Gen Physiol. (January 1977)

²⁰Bilbey DL, Prabhakaran VM Muscle cramps and magnesium deficiency: case reports Can Fam Physician. (1996 Jul)

²¹Cinar V, Polat Y, Baltaci AK, Mogulkoc R. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion. Biol Trace Elem Res. (April 2011)