4Fem

4Fem, from Vitobest®, it is a product specifically developed for contribute to improving female sexual health.

Its advanced formula and highest quality components help to improve libido and act on the nervous system, calming stress.

It is a completely safe product and is backed by numerous scientific studies.

The key: stress control and good hormonal balance.

One of the main causes of lack of sexual desire in women is stress caused by the current pace of life and sedentary lifestyle.

The advanced formula of 4Fem, from

Vitobest®, contains saffron and ashwagandha, which contribute to effectively reducing stress.

The Angelica sinensis and the Wild yam They contribute to hormonal balance, improving sexual appetite.

4Fem, from Vitobest®, is composed of:

Angelica sinensis (1% ligustilide):

• It contains flavonoids, phytosterols, minerals (iron, magnesium, potassium) and vitamin A, B3, C, and E, which can influence the production of estrogen, essential for maintaining sexual desire at a satisfactory level.
• It is also characterized by improving arousal during menopause.
• Increases blood supply to the reproductive organs².
• Increases the production of nitric oxide which improves lubrication and libido³.
• Acts as a flow regulator, vasodilator and hormonal balancer.
• Its high content of ligustilide improves the function of the internal uterine tissue³.

MacaFull® (0.6% macamides and macaenes):

• Numerous studies show that maca positively modulates sexual behavior and increases libido⁵.
• It is especially effective during menopause⁴.
• Maca improves thyroid function, resulting in better energy levels, and increases dopamine levels⁷.
• Most of the testosterone in the blood is bound to the sex hormone binding globulin (SHBG) protein, while the portion that is not bound to it is known as "free testosterone", and it is precisely this that maca can influence⁶.

Dioscorea villosa (Wild Yam) (16% diosgenin):

The wild yam is rich in diosgenin, chemically similar to progesterone, and its rate decreases in some situations (menopause period, premenstrual period). It helps to improve:

• Menopausal syndromes.
• PMS (premenstrual syndrome).
• Osteoporosis.
• Increases energy and sexual desire in both men and women.

Dry extract of damiana leavesDamiana):

• With high content in polyphenols, glycosides and terpenes.
• Energizing (adaptogen).
• Stress control.
• Helps improve sexual function in women¹.

Ashwagandha:

• Powerful adaptogen⁹.
• Stress and cortisol control, inducing mental and physical balance⁹.

Saffron:

• Dopamine increase⁸.
• Reduces stress and improves mood.

Vitobest® used for this supplement vegetable capsules (VegeCaps) suitable for vegan diets and free of titanium dioxide.

Bibliography:

¹"Ethnobotany, phytochemistry, and bioactivity of the genus Turnera (Passifloraceae) with a focus on damiana". Damiana Katarzyna Szewczyk a, Christian Zidorn b, n.

²Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways Yu-Wen Su, Wen-Fei Chiou, Shiou-Huei Chao, Meng-Hwan Lee, Chien-Chih Chen, Ying-Chieh Tsai.

³Du J, Bai B, Kuang X, Yu Y, Wang C, Ke Y, Xu Y, Tzang AHC, Qian ZM. Ligustilide inhibits spontaneous and agonists- or K+ depolarization-induced contraction of rat uterus. J Ethnopharmacol. 2006;108(1):54–8. doi: 10.1016/j.jep.2006.04.011.

⁴"Study of the adaptogenic effect of Lepidium peruvianum Chacón ("maca") in experimental animals". 2003. Quispe, E. et al. In: 2nd International Congress - II Peruvian Congress of Medicinal Plants, Lima - Peru. Book of Memories. pp. 162.

⁵"Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands". Gustavo F. Gonzales Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and High Altitude Research Institute, Cayetano Heredia Peruvian University, Honorio Delgado 430, Lima 31, Peru.

⁶"Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men". G F Gonzales 1, A Córdova, K Vega, A Chung, A Villena, C Góñez, S Castillo.

⁷"Maca ("Lepidium meyenii "Andean Functional Food: Bioactive, Biochemical and Biological Activity" by Emilio Yábar Villanueva, Vilma Reyes De La Cruz.

⁸"Study on Saffron". 2002. Herrero Sanchez, G., Polytechnic University School - Industrial-Agricultural-Computer-Architecture. University of Zaragoza.

⁹"Pharmacological overview of Withania somnifera, the Indian Ginseng". 2015. Nawab J.D. et al. Cellular and Molecular Life Sciences, Volume 72, Issue 23, pp 4445–4460.