NAD+ & Pterostilbene

Advanced formula with NR (direct precursor of NAD+) and pterostilbene of high purity to revitalize body and mind.

• Naturally increases cellular energy and daily vitality.
• Combats physical and mental fatigue in situations of high wear and tear.
• Promotes clarity, focus, and cognitive performance.
• Contributes to a better recovery after physical effort or stress.
• Powerful antioxidant action that protects cells from daily damage.
• Helps to maintain an active metabolism and healthy aging.
• Supports cardiovascular, muscular and brain health.

NAD+ & Pterostilbene, from Vitobest®: the new generation of cellular supplements.

The current pace of life, stress, and the passage of time reduce the levels of NAD+, an essential coenzyme for producing energy in our cells. This natural decline is directly related to fatigue, loss of concentration, and accelerated aging^1,2,9.

Vitobest® has developed a unique formula that combines:

1. NR (nicotinamide riboside): direct precursor of NAD+, which helps to restore cellular energy levels^1,2.
2. Pterostilbene (99% active polyphenols): new generation antioxidant, with high bioavailability and greater stability than resveratrol^3,4.

Together, these molecules create a synergy that multiplies vitality, protects against aging, and enhances recovery capacity^5,6.

How does it work?

NR (nicotinamide riboside): the engine of NAD+.

• Restores the levels of NAD+, key for cellular energy^1,2.
• Promotes the production of ATP, the "energy currency" of the cell^5,6.
• Supports cellular repair and regeneration processes^2.9.
• Compensates for the natural fall of NAD+ associated with age⁹.

Pterostilbene: the intelligent antioxidant.

• High concentration (99% active polyphenols) for maximum effectiveness³.
• More stable and bioavailable than resveratrol⁴.
• Powerful antioxidant and anti-inflammatory action^7,8.
• Promotes young and efficient mitochondria⁵.

The synergy of NAD+ & Pterostilbene.

• They enhance cellular energy and metabolism together^1.5.
• They strengthen the defense systems against premature aging^7,8.
• They promote mental clarity, physical performance, and recovery^2,9,11.
• They offer comprehensive support for vitality and longevity^1,3,5.

Main directions:

• Persistent fatigue or lack of energy^9,10.
• Difficulty concentrating or maintaining focus^2,9,11.
• Prolonged physical or mental stress^6,7.
• Slow recovery after exercise or overload⁵.
• Support in healthy aging and in the prevention of mitochondrial dysfunction^1,2,3,9.

NAD+ & Pterostilbene, cellular energy and longevity.

Vitobest® used for this supplement vegetable capsules (VegeCaps) suitable for vegan diets and free of titanium dioxide.

Bibliography:

¹This is not a Spanish phrase that needs translation. It appears to be a citation of authors' names (Nunnari J, Suomalainen A) in a piece of academic literature. Mitochondria: In sickness and in health. Cell. 2012;148(6):1145–1159.

²Wallace DC. Mitochondrial Genetic Medicine. Nat Genet. 2018;50(12):1642–1649.

³BN Ames. A low intake of micronutrients may accelerate the degenerative diseases of aging.. PNAS. 2006;103(47):17589–17594.

⁴Sanderson SM, Gao X, Dai Z, Locasale JW. Metabolism and signaling of dietary metabolites. Nat Rev Mol Cell Biol. 2020;21(10):585–602.

⁵Radak Z, et al. Exercise, Oxidative Stress and Hormesis. Ageing Res Rev. 2008;7(1):34–42.

⁶Nicholls DG, Ferguson SJ. Bioenergetics 4. Academic Press; 2013.

⁷McEwen BS. Effects of stress mediators: role of the brain. Ann N Y Acad Sci. 1998;840:33–44. (Note: This is a citation for an article from the Annals of the New York Academy of Sciences. The numbers indicate the volume and page range. There is no need to translate this, as it remains the same in both languages.)

⁸Harman D. Free Radical Theory of Aging: An Update. Ann N Y Acad Sci. 2006;1067:10–21.

⁹Picard M, et al. The mitochondrial basis of aging and age-related disease. Curr Biol. 2016;26(21):R832-R843.

¹⁰Forsyth LM, et al. Therapeutic effects of oral NADH in chronic fatigue syndrome. Ann Allergy Asthma Immunol. 1999;82(2):185–191.

¹¹Rex A, Fink H. Effects of NADH on memory and attention in rats. Neurosci Biobehav Rev. 2000;24(1):13–24.